Interdisciplinary Interface Training Program (IITP) Grant - Previous Awardees

Year Award Recipient Mentor Project Title
2025 Fangfang Guo Jun Li & Sharon Stack Decoding the Molecular Landscape of Native American and Latin American Cancers: A Multi-Omics Perspective
2025

Gaeun Kim

Yichun Wang & Xin Lu Dendritic Cell-Derived Small Extracellular Vesicles for Enhanced Adoptive T Cell Transfer Therapy through T Cell Activation and Immune Checkpoint Blockade
2025 Maksym Zarodniuk Meenal Datta & Jun Li Transcriptional Regulation of Glioblastoma-Associated Fibroblasts
2024 Alice Burchett Meenal Datta & Tengfei Luo Establishing a novel spheroid model in microgravity to elucidate immunomechanical reciprocal regulation in glioblastoma
2024 Shiyu Wang Xin Lu & Brian Blagg Enhancing CAR-T Immunotherapy with Isoform-Selective HSP90 Inhibition
2024 Wanrui Wang Sharon Stack & Brian Blagg Novel Strategy to Block Obesity Induced SREBP1 Activity Via HSP90β-Selective Inhibition for Ovarian Cancer
2023 Jensen Amens Pinar Zorlutuna & Sharon Stack Investigating the Effect of Chemotherapeutics on Normal Breast Fibroblast ECM Production
2023 Sarah Nano Glen Niebur & Laurie Littlepage Mechanical loading effects on breast cancer proliferation, migration, and dormancy and bone mechanoadaptation in a human bone metastatic environment
2023 Ziyu Zeng Xin Lu & Jun Li Cross-Species Single-Cell Analysis Uncovers Evolution of Neutrophil Heterogeneity in Neuroendocrine Prostate Cancer
2022 Leah (Cossin) Lund Kate White & Donny Hanjaya-Putra Characterizing the relationship between tumor microenvironment stiffness and pH dynamics in cancer
2022 Janeala Morsby Bradley Smith & Meenal Datta Monitoring Glioblastoma Hypoxia Development Using a Novel Carbonic Anhydrase IX Targeted Near Infrared Highly Stable and Renal Clearable Probe for Improved Patient Therapy Outcome 
2022 Jun Yang Pinar Zorlutuna & Brian Blagg 3D Age-Related Breast Cancer Model with Mouse Extracted Collagen for Novel Drug Screening
2021 Loan Duong Xin Lu & Sangpil Yoon “Off-the-shelf” Novel Chimeric Antigen Receptor (CAR) NK Cell Therapy for Lethal Prostate Cancer
2021 Courtney Flatt Laurie Littlepage, Glen Niebur & Olaf Wiest Evaluating Cxcr2 signaling as a therapeutic target in breast cancer bone metastasis
2021 Kyler Pugh Brian Blagg & Sharon Stack The Synthesis and Biological Evaluation of Grp94 Inhibitors: A Non-toxic Therapeutic Approach Against Cancer Metastasis
2020 Samantha Golomb Siyuan Zhang & Shaun Lee Engineered gut microbiota as an adjuvant for cancer immunotherapy and metastasis
2020 Francisco Huizar Jeremiah Zartman & Brandon Ashfeld Accelerating Preclinical Testing of Dual-Specificity Protein Kinase Inhibitors for Triple Negative Breast Cancer Therapeutics with an In Vivo High-Content and High-Throughput Phenotypic Platform
2020 Maria Cristina Miranda Vergara Laurie Littlepage & Glen Niebur Evaluating Cxcr2 activation as a therapeutic vulnerability in ER+ breast cancer metastasis to bone
2019 Laura Alderfer Donny Hanjaya-Putra & Laurie Littlepage Employing the Breast Cancer Microenvironment for Biomimetic Lymphatic Vessel Engineering to Resolve Cancer-Related Lymphedema
2019 Nicole Hudson Rebecca Whelan & Sharon Stack In-Depth Characterization of Exosomes in Metastatic Ovarian Carcinoma in Young vs Aged Patients
2019 Sharif Rahmy Xin Lu & Brian Blagg Sensitizing Advanced Prostate Cancer to Immunotherapy by Isoform-Selective HSP90 Inhibitors
2018 Tyler Finamore Ryan Roeder & Laurie Littlepage Disruption of Microcalcification-Induced Tumorigenesis Using Bisphosphonate-Functionalized Gold Nanoparticles
2018 Elizabeth Harper Sharon Stack & Brian Blagg The Role of Aging Peritoneum on Ovarian Cancer Metastasis
2017 Marwa Asem Sharon Stack, Matthew Ravosa, & Pinar Zorlutuna Intra-peritoneal Mechanobiology and Tumor:Host Crosstalk in Ovarian Cancer
2017 Austin Boucher Richard Dahl, Karen Cowden-Dahl, & Ryan Roeder Targeting miRNAs to Combat Immune Suppression in Cancer
2017 Angela Poffenberger Brian Baker, Brandon Ashfeld, & Caroline Le Poole Structural Characterization of Vitiligo Associated T Cell Receptor: Towards the Development of Improved Melanoma Immunotherapy
2017 Casey Stefanski Jenifer Prosperi & Matthew Webber Doxorubicin-loaded Nanoparticles for Treatment in Chemoresistant Breast Cancer Cells
2016 Pavel Brodskiy Jeremiah Zartman & Danny Chen Next-generation high-content analysis (HCA) facilitating integrated drug synthesis and mechanistic characterization
2016 Alyssa Lesko Jenifer Prosperi & Jeremiah Zartman Adenomatous Polyposis Coli Mediates the Cytoskeleton to Regulate Cell Motility
2016 Felicia Roland Bradley Smith & Ryan Roeder Targeted Nanoparticles for Multimodal Imaging and Guided Surgery of Ovarian Cancer
2016 Kimberly Curtis Glen Niebur & Laurie Littlepage The Effects of LMMS on Breast Cancer Metastasis in Bone
2016 Ann Zeleniak Reginald Hill & Amanda Hummon Identification of Key Metastatis Promoting Peptides for the Proteomes of Stromal-Treated & MTSS1-Deficient Pancreatic Cancer Cells
2015 Charissa Quinlan & David Omstead Basar Bilgicer & Rafat Abonour Engineering Dual Drug Loaded Liposomal Nanoparticles for the Treatment of Multiple Myeloma
2015 Kevin Rodriquez Jeremiah Zartman & Brandon Ashfeld Phosphorous Mediated Cycloadditions Towards the Synthesis of Spirooxindole Alkaloids for the Treatment of Breast Cancer with Brain Metastasis
2015 Sindu Preetham Burugupally David Hoelzle & Siyuan Zhang Development of a novel microdevice to understand the link between tumor cell mechanical heterogeneity and cancer invasiveness
2015 Zhicong Zeng Zachary Schultz & Sharon Stack Correlating Extra-Cellular Matrix Mechanics In The Peritoneum With Age-Associated Onset Of Ovarian Cancer Metastasis
2014 Ricardo Moreno-Romero Laurie Littlepage & Glen Niebur A Novel Bone Bioreactor Used to Model Bone Metastasis Ex Vivo
2014 Patricia Skallos Siyuan Zhang & David Hoelzle Quantitative Investigation of the Dynamic Crosstalk between Brain Metastatic Cells and Brain Stromal Microenvironment
2014 Wei Huang Reginald Hill & Amanda Hummon Identification of Novel Stromal Peptides Regulating Chemoresistance of Pancreatic Cancer
2014 Volker Kurz & Eamonn Kennedy Gregory Timp, Jenifer Prosperi, & Tetsuya Tanaka Defining a Molecular Profile Associated with Breast Cancer Metastasis by a Nanopore
2013 Danny Taller & Katherine Richards Reginald Hill & David Go Rapid Separation of Vesicles by Surface Acoustic Wave-inspired Microfluidics for Early Detection and Diagnosis of Pancreatic Cancer
2013 Lisa Cole & Tracie McGinnity Ryan Roeder & Tracy Vargo-Gogola Contrast-enhanced X-ray detection of breast microcalcifications in a murine model of radiographically dense mammary tissue
2013 Christopher Suarez Laurie Littlepage & Sunil Badve Novel preclinical animal models of chemotherapy resistance using patient-derived breast tumor xenografts
2013 Shaoshi Gao Kevin Vaughan & Reginald Hill Combining Microtubule Stabilizing Agents with Mitotic Kinase Inhibitors To Improve Treatment of Pancreatic Cancer