Cancer Cure Venture Grant

The Cancer Cure Venture (CCV) Grant, made possible by the Walther Cancer Foundation, is intended to support innovative research projects conceived at the interdisciplinary interface of biology, chemistry, engineering, genetics and medicine. 


Overall Goals

  • Stimulate novel multi-disciplinary integrative cancer research
  • Seed collaborative interactions between at least 2 scientific fields
  • Provide cross-disciplinary training environment for post-doctoral fellows
  • Generate high-quality preliminary data for extramural application 



  • Open to all faculty members of HCRI (click here for membership information
  • Requires multi-disciplinary collaboration between at least two distinct HCRI research groups from disparate disciplines
  • High likelihood to generate preliminary data of sufficient quality and quantity to support an extra-mural cancer focus grant application
  • Must provide high-quality training opportunity for post-doctoral fellow that crosses discipline boundaries
  • Publications that result from data collected under this mechanism must acknowledge the Walther Cancer Foundations and grant proposals that result from said data should be affiliated with HCRI in Cayuse



  • Funding is for two years (up to $100,000 total cost) 
    • Shared Post-doctoral salary of $61,440 ($48,000 salary + $13,440 fringe)
    • Shared resource funds up to $10,000 (may only be spent in a Notre Dame, IU, or Purdue shared resource facility)
    • Supplies $30,000
  • Funding for year two with the same budget limits only if investigator-defined targeted deliverables are met in year 1


  • Full Applications are due by 11:59 p.m. EDT on May 31, 2021.
  • Applications will be reviewed by the end of June.
  • Application notices will be sent out by mid-July.


Proposal Format and Requirements

  • Formatting
    • Single spaced
    • Arial 11 font or larger
    • Margins 0.6" or larger
    • Assemble all sections below into a single PDF for submission
  • Cover Page (1 page)
    • Project Title
    • Corresponding Principal Investigator name, department, position/title, email
    • Co-Investigator(s) name, institution, department, position/title, email
    • Post-doctoral Fellow name, institution, department, position/title, email (if applicable)
    • Supplemental Data (please include on cover page)
      • Human subjects: 
        • Yes__ No__
        • Approval number_____ Approval Pending_____
      • Vertebrate Animals: 
        • Yes__ No__ 
        • Approval number_____ Approval pending_____ 
      • Applicants will: 
        • Apply for HCRI membership or are current members         Yes___ No___ 
        • Acknowledge WCF on related publications                        Yes___ No___ 
        • Designated HCRI for F&A return on related external grants  Yes___ No___ 
  • Abstract (1 page, up to 30 lines of text)
    • Provide a succinct overview of the proposed project. Include the relevance to cancer, the broad objectives and specific aims, an overview of the research design and methods, and a brief description of the inter-disciplinary training environment. 
  • Research Plan
    • Significance/Background (1 page)
      • relevance of proposed collaboration to a cancer-specific research problem 
    • Research Design (up to 3 pages) include: 
      • overview of conceptual framework, design, methods, analyses 
      • how the collaboration will develop novel concepts and/or approaches 
      • how the application will generate preliminary data for an extramural application 
      • must specify clearly defined targeted deliverables, with timeline (in at least bi-annual increments)
    • References (include references on separate page following research plan. References not included in page limit.)
    • Biosketch (up to 3 pages) from each team member  
  • Collaboration Plan (1 pages)
    • Describe the interdisciplinary team, distinct contribution and advantage of each partner to team, and inter-group communication plan 
  • Training/Mentoring Plan (1 page)
    • Describe the specific mentoring and career development activities for the post-doctoral fellow and the advantages of the interdisciplinary training opportunity. 
  • Budget
    • Provide a budget for 2 years for up to $100,000 direct costs per year as follows: 
      • (A) Post-doctoral fellow – up to $61,440 for salary and fringe benefits. 
      • Note: funds are intended to support one post-doctoral fellow to perform shared research between 2 or more labs. Partial support of 2 or more post-docs from individual collaborator labs is not intended. 
      • (B) Supplies – up to $30,000 for research supplies 
      • (C) Shared resource funding – up to $10,000 to be used only in a Notre Dame (, IU, or Purdue shared resource/core facility (
      • (D) Budget justification 
  • Progress Report
    • A one-page progress report is due three weeks prior to the end of year 1 funding. The Progress Report must outline accomplishments during the initial funding relative to anticipated deliverables as defined in the proposal. Notice - Release of year 2 funds is contingent on meeting targeted deliverables.


Evaluation Criteria

  • Evidence of inter-disciplinary collaboration
  • Overall scientific excellence
  • Cancer relevance of project 
  • Well defined deliverables
  • Excellence of post-doctoral training plan
  • Innovation
  • Potential to generate data for competitive extra-mural application within 2 year funding period
    • Note: this funding mechanism is intended to result in data of sufficient quantity and quality to support an extramural cancer-focused grant application at the end of the 2- year support period. Renewal requests for continuation of the project beyond the 2-year timeframe will not be considered. 



For information on the CCV Awards, please contact Andy Bullock.