Mike and Josie Harper Cancer Research Institute

Innovative Drug Discovery and DesignConnecting Research Strengths Across the State Collaborative Teams Drive Innovation Developing Imaging Tools for Cancer Detection and TreatmentEstablishing Preclinical Models for Drug TestingDeciphering Distinct Molecular Signatures of Cancer



Investigators in the Harper Cancer Research Institute (HCRI) are dedicated to conducting innovative and integrative research that confronts the complex challenges of cancer.  Our programmatic structure fosters multi-disciplinary cancer research by promoting interactions among research groups with distinct expertise and by training young scientists to work across scientific fields. Clinical partnerships provide key translational insight and strengthen the mission of discovery.


HCRI Mission Statement:

Innovative and integrative research confronting the complex challenges of cancer


Investigating aggressive, lethal breast tumors of Kenyan cancer patients

February 27, 2015 • Categories: Announcements and Homepage

Maggie Kerper

Maggie Kerper came to college interested in science, but really developed a passion for the field after taking her first college-level science classes. After transferring to Notre Dame as a sophomore, she decided to find ways to explore science outside of the classroom.   

Kerper began working with Laurie Littlepage, Campbell Assistant Professor of Cancer Research in the Department of Chemistry and Biochemistry, during the spring of her sophomore year. “I went to an extra credit talk given by Prof. Littlepage and was so impressed and interested in her work. I had no idea cancer research opportunities like this existed on campus,” she explains. “I immediately felt drawn to get involved. I can’t think of any other field that I would feel the sort of gratification and drive to work harder than the cancer field.”

Father Theodore Hesburgh of Notre Dame dies at age 97

February 27, 2015 • Categories: Announcements and Homepage




Rev. Theodore M. Hesburgh, C.S.C., president of the University of Notre Dame from 1952 to 1987, a priest of the Congregation of Holy Cross and one of the nation’s most influential figures in higher education, the Catholic Church and


national and international affairs, died at 11:30 p.m. Thursday (Feb. 26) at Holy Cross House adjacent to the University. He was 97.

“We mourn today a great man and faithful priest who transformed the University of Notre Dame and touched the lives of many,” said Rev. John I. Jenkins, C.S.C., Notre Dame’s president. “With his leadership, charisma and vision, he turned a relatively small Catholic college known for football into one of the nation’s great institutions for higher learning." Read more...

Thanks be to grads! Graduate Student Appreciation Week begins

February 26, 2015 • Categories: Announcements and Homepage


We love our grad students all year long, but this week we’re taking extra time to show it! With parties, food, freebies, discounts, and most importantly, time to hang out with fellow grad students. Come out and enjoy a week of celebrating you!


IUSM- SB SEMINAR: Alyssa Lesko, Graduate Student

Mon Mar 2, 2015 4:00PM - 5:00PM • 101 Harper Hall Multipurpose Room • Calendars: Homepage and HCRI Events Calendar

Alyssa Lesko, Graduate student from the Prosperi lab, is giving a seminar at 4:00 in 101 Harper Hall. …

SEMINAR: Dr. David Piwnica-Worms, MD Anderson

Tue Mar 3, 2015 • Harper Hall, Multipurpose Room • Calendars: Homepage and HCRI Events Calendar

Dr. David Piwnica-Worms will be visiting Notre Dame on March 2 and 3 and will be holding a seminar titled, "Illuminating Signaling Pathways and Metabolic Stress In Vivo."   Read more...

Research Like a Champion

Fri Mar 6, 2015 • science.nd.edu/ResearchLikeaChampion • Calendars: Homepage and HCRI Events Calendar

Do you want to cure cancer? 

Participate in the 2nd annual Research Like a Champion competition. Undergraduate and graduate students from all colleges are invited to submit proposals for innovative projects looking into the causes, treatment and prevention of cancer. Last year, three teams won research awards of $12,500. Read more...