HCRI Biorepository Director; Research Assistant Professor of Chemistry & Biochemistry at the University of Notre Dame
University of Notre Dame
Zonggao Shi earned his doctorate in Cancer Pathology at Fudan University (Shanghai, China) in 2001 and is director of the Biosample Repository at HCRI. The primary function of the Repository is the procurement and management of normal and neoplastic tissues and cell lines from humans and experimental animals. In addition to cryopreservation and common storage capability, the repository is home to basic histopathology equipment, Veridiam tissue arrayer for tissue microarray (TMA) construction, Arcturus XT Laser Capture Microdissection system for accurate sampling, and Aperio ScanScope CS for digital pathology. This shared core facility welcomes all types of service requests and collaborations.
Beyond his role in biorepository service, Dr. Shi continues his research pursuits in cancer molecular pathology. His long term efforts are focused on better understanding of the molecular mechanisms of cancer metastasis, particularly with squamous cell carcinoma of the oral cavity as a model system. His current studies are exploring the role of microRNAs and their mechanisms of action in regulating cell adhesion, invasion and cancer metastasis. Dr. Shi is also interested in developing more efficient cellular and animal models to enhance the study of cancer metastasis.